PTGIS

Basic Information

Gene Symbol	PTGIS
Entrez Id	5740
Position	chr20:48120411..48184707
Description	prostaglandin I2 (prostacyclin) synthase
Gene type	protein-coding

SNP Information

SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*
rs111793493	20:48178833	T/C	PTGIS	intron	0.704	1.03365	0.0484	0.4934		3a
rs112219753	20:48155793	T/G	PTGIS	intron	0.744	0.93557	0.0349	0.05635		5
rs112392428	20:48137163	A/G	PTGIS	intron	0.626	1.00743	0.0311	0.8116		7
rs112853036	20:48134293	T/C	PTGIS	intron	0.619	0.96242	0.0427	0.3707		5
rs113110790	20:48138051	T/C	PTGIS	intron	0.705	1.04938	0.0513	0.3472		5
rs116853191	20:48153842	A/G	PTGIS	intron	0.631	1.03521	0.0608	0.5688		2b
rs116939356	20:48184560	T/G	PTGIS	intron,near-gene-5	0.840	0.95266	0.0208	0.01989		4
rs11696748	20:48128139	T/C	PTGIS	intron	0.998	0.94214	0.0122	1.134E-6		6
rs117140207	20:48133384	T/C	PTGIS	intron	0.750	0.90692	0.0564	0.08317		7
rs117222401	20:48154723	T/C	PTGIS	intron	0.719	0.87845	0.0651	0.04666		7
rs117226622	20:48127269	T/C	PTGIS	intron	0.755	1.01552	0.0652	0.8136		4
rs117234571	20:48141334	A/C	PTGIS	intron	0.684	0.95849	0.0539	0.4308		7
rs117238134	20:48133817	A/G	PTGIS	intron	0.746	1.04718	0.0660	0.4848		5
rs117769190	20:48154718	A/G	PTGIS	intron	0.740	1.02603	0.0232	0.2674		7
rs117800589	20:48141239	T/C	PTGIS	intron	0.673	1.04582	0.0586	0.4447		6
rs117927958	20:48154547	T/C	PTGIS	intron	0.929	0.97844	0.0232	0.3485		6
rs11906639	20:48134616	T/C	PTGIS	intron	0.744	1.03097	0.0497	0.5392		7
rs11908529	20:48183215	A/G	PTGIS	intron,near-gene-5	0.873	0.95285	0.0215	0.02465		5
rs12165262	20:48153049	A/G	PTGIS	intron	0.725	1.07713	0.0259	0.004106		7
rs12625166	20:48167203	T/G	PTGIS	intron	0.980	1.01704	0.0239	0.4798		7
rs13039739	20:48125015	A/G	PTGIS	intron	0.986	1.06354	0.0125	8.459E-7		4
rs13433380	20:48153395	A/G	PTGIS	intron	0.772	0.92747	0.0263	0.004125		6
rs139610481	20:48177341	A/G	PTGIS	intron	0.609	1.01694	0.0669	0.802		-
rs141502369	20:48150969	T/C	PTGIS	intron	0.732	1.05950	0.0645	0.3708		-
rs143162773	20:48142512	A/G	PTGIS	intron	0.654	0.99471	0.0715	0.9408		-
rs144332344	20:48135276	A/G	PTGIS	intron	0.751	1.06056	0.0495	0.235		-
rs148992383	20:48128880	A/G	PTGIS	intron	0.742	0.91475	0.0412	0.03044		-
rs149490960	20:48180360	A/G	PTGIS	intron	0.622	1.12042	0.0642	0.07635		-
rs149648985	20:48176523	A/G	PTGIS	intron	0.661	1.04728	0.0438	0.2919		-
rs149811032	20:48150396	A/G	PTGIS	intron	0.767	0.92164	0.0269	0.002403		-
rs150660754	20:48138359	A/G	PTGIS	intron	0.744	0.94337	0.0612	0.3404		-
rs150818638	20:48164617	T/C	PTGIS	intron	0.617	1.02593	0.0671	0.7032		-
rs150944682	20:48130173	T/C	PTGIS	intron	0.727	1.04509	0.0428	0.3026		-
rs184754529	20:48154848	T/C	PTGIS	intron	0.693	0.90937	0.0640	0.1376		-
rs35193371	20:48126879	T/C	PTGIS	intron	0.997	1.06322	0.0122	5.208E-7		6
rs4810965	20:48154079	A/G	PTGIS	intron	0.872	0.97414	0.0180	0.1458		7
rs491490	20:48175678	A/G	PTGIS	intron	0.810	0.99770	0.0126	0.8585		5
rs492195	20:48120999	A/C	PTGIS	untranslated-3	0.996	1.05707	0.0117	2.279E-6		6
rs493694	20:48183130	T/C	PTGIS	intron,near-gene-5	0.870	0.98926	0.0113	0.3412		5
rs495146	20:48130328	T/C	PTGIS	intron	0.994	1.06428	0.0120	2.128E-7		2b
rs496962	20:48136724	T/C	PTGIS	intron	0.833	0.94290	0.0153	0.0001211		7
rs497069	20:48136682	T/C	PTGIS	intron	0.822	0.94611	0.0150	0.0002176		5
rs504974	20:48152343	A/G	PTGIS	intron	0.926	1.02030	0.0231	0.3825		7
rs508757	20:48138971	T/C	PTGIS	intron	0.916	1.05527	0.0142	0.0001446		6
rs511073	20:48182021	A/G	PTGIS	intron	0.910	0.97971	0.0151	0.1745		6
rs515633	20:48163144	A/G	PTGIS	intron	0.959	1.01461	0.0234	0.5357		6
rs522962	20:48143362	T/C	PTGIS	intron	0.944	1.00803	0.0110	0.4643		5
rs60169668	20:48132571	A/C	PTGIS	intron	0.805	0.94318	0.0684	0.3925		5
rs6019879	20:48130628	T/C	PTGIS	intron	0.993	0.93810	0.0121	1.388E-7		6
rs6019902	20:48178213	A/G	PTGIS	intron	0.865	0.97658	0.0148	0.1079		7
rs6090996	20:48133782	A/G	PTGIS	intron	0.896	0.94724	0.0143	0.0001459		5
rs6090997	20:48142132	A/T	PTGIS	intron	0.897	1.01278	0.0218	0.5586		6
rs6090998	20:48142133	A/T	PTGIS	intron	0.850	1.01126	0.0220	0.6094		6
rs6091000	20:48152675	T/C	PTGIS	intron	0.772	1.07799	0.0262	0.004193		6
rs61013127	20:48133549	A/G	PTGIS	intron	0.771	1.04687	0.0143	0.001339		6
rs61322884	20:48156249	A/G	PTGIS	coding-synon	0.662	0.97482	0.0396	0.5189		7
rs62209222	20:48160782	T/C	PTGIS	intron	0.637	0.97025	0.0696	0.6644		5
rs62209224	20:48177154	T/C	PTGIS	intron	0.612	0.99661	0.0381	0.9296		7
rs66515906	20:48177868	A/G	PTGIS	intron	0.790	0.98946	0.0163	0.5177		7
rs707529	20:48181035	A/G	PTGIS	intron	0.802	1.00662	0.0119	0.5796		7
rs7267348	20:48131036	T/C	PTGIS	intron	0.993	0.93782	0.0121	1.182E-7		5
rs7273247	20:48170236	T/C	PTGIS	intron	0.772	1.08970	0.0569	0.1311		7
rs729824	20:48127176	T/C	PTGIS	intron	0.997	0.94082	0.0122	5.938E-7		2b
rs73124173	20:48139768	A/C	PTGIS	intron	0.791	0.89808	0.0451	0.01721		7
rs73124177	20:48156373	A/G	PTGIS	intron	0.735	1.02532	0.0232	0.2826		6
rs73124179	20:48162539	A/G	PTGIS	intron	0.721	1.03097	0.0223	0.171		6
rs73124192	20:48177403	A/G	PTGIS	intron	0.744	0.96889	0.0254	0.214		5
rs73126221	20:48184048	A/G	PTGIS	intron,near-gene-5	0.783	0.95514	0.0332	0.1669		5
rs75416472	20:48176141	T/C	PTGIS	intron	0.661	1.02153	0.0305	0.4861		5
rs76998991	20:48147756	T/C	PTGIS	intron	0.685	0.98580	0.0385	0.7097		6
rs77317874	20:48132398	T/C	PTGIS	intron	0.812	0.93557	0.0403	0.09784		2b
rs77401275	20:48134818	A/G	PTGIS	intron	0.666	0.97658	0.0416	0.5689		7
rs77823273	20:48136683	A/G	PTGIS	intron	0.709	1.03863	0.0497	0.446		5
rs78134375	20:48127380	T/C	PTGIS	intron	0.729	0.95628	0.0429	0.297		4
rs78865809	20:48183370	T/C	PTGIS	intron,near-gene-5	0.766	0.96551	0.0371	0.3437		5
rs80031368	20:48154367	A/G	PTGIS	intron	0.701	0.96715	0.0445	0.4525		7
rs8115305	20:48147421	T/C	PTGIS	intron	0.682	1.07756	0.0422	0.07638		7
rs8121749	20:48128589	A/G	PTGIS	intron	0.996	0.94101	0.0122	5.707E-7		6
rs927068	20:48177974	T/G	PTGIS	intron	0.874	0.96512	0.0132	0.007257		5
rs963455	20:48179993	T/C	PTGIS	intron	0.863	1.02388	0.0122	0.05324		4
SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*

Note: RegulomeDB score^*

score	supporting data	score	supporting data
1a	eQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak	6	other
2a	TF binding + matched TF motif + matched DNase Footprint + DNase peak	5	TF binding or DNase peak
1b	eQTL + TF binding + any motif + DNase Footprint + DNase peak	4	TF binding + DNase peak
2b	TF binding + any motif + DNase Footprint + DNase peak	3b	TF binding + matched TF motif
1c	eQTL + TF binding + matched TF motif + DNase peak	1f	eQTL + TF binding / DNase peak
2c	TF binding + matched TF motif + DNase peak	3a	TF binding + any motif + DNase peak
1d	eQTL + TF binding + any motif + DNase peak	1e	eQTL + TF binding + matched TF motif

CNV Information

The gene is not affected by CNV!

eQTL Information